学习经历
2010.09-2014.07 中国科学院大学 生物化学与分子生物学
2008.09-2010.06 武汉大学 微生物
2004.09-2008-07 哈尔滨工业大学 生物工程
工作经历
2022.01至今 上海交通大学系统生物医学研究院 副研究员
2017.04-2021.12 上海交通大学系统生物医学研究院 助理研究员
2010.10-2017.03 上海交通大学 博士后
1.蛋白质芯片技术的开发及应用
2.高效蛋白质研究方法的开发
(1) Huan Qi; Jun-biao Xue; Dan-yun Lai; Ang Li; Sheng-ce Tao. Current Advances in Antibody-Based Serum Biomarker Studies: From Protein Microarray to Phage Display. Proteom. Clin. Appl. 2022, 16 (6), 2100098.
(2) Lingyun Chen; Pengfei Pang; Huan Qi; Keqiang Yan; Yan Ren; Mingliang Ma; Ruyin Cao; Hua Li; Chuansheng Hu; Yang Li; Jun Xia; Danyun Lai; Yuliang Dong; Hewei Jiang; Hainan Zhang; Hong Shan; Shengce Tao; Siqi Liu. Evaluation of Spike Protein Epitopes by Assessing the Dynamics of Humoral Immune Responses in Moderate COVID-19. Frontiers in immunollogy 2022, 13, 770982.
(3) Huan Qi; Mingliang Ma; He-wei Jiang; Jian-ya Ling; Ling-yun Chen; Hai-nan Zhang; Dan-yun Lai; Yang Li; Zi-wen Guo; Chuan-sheng Hu; Shu-juan Guo; Qing-feng Meng; Yan Ren; Xiao Yang; Wei Wang; Jie Zhou; Xiao-dong Zhao; Hua Li; Sheng-ce Tao. Systematic Profiling of SARS-CoV-2 Specific IgG Epitopes at Amino Acid Resolution. Cellular & Molecular Immunology 2021, 18 (4), 1067–1069.
(4) Huan Qi; Mingliang Ma; Chuansheng Hu; Zhao-wei Xu; Fan-lin Wu; Nan Wang; Dan-yun Lai; Yang Li; Hainan Zhang; He-wei Jiang; Qing-feng Meng; Shujuan Guo; Yani Kang; Xiaodong Zhao; Hua Li; Sheng-ce Tao. Antibody Binding Epitope Mapping (AbMap) of Hundred Antibodies in a Single Run. Mol. Cell. Proteomics 2021, 20, 10059.
(5) Mingliang Ma; Huan Qi; Chuansheng Hu; Zhao-wei Xu; Fan-lin Wu; Nan Wang; Dan-yun Lai; Yang Li; Hainan Zhang; He-wei Jiang; Qing-feng Meng; Shujuan Guo; Yani Kang; Xiaodong Zhao; Hua Li; Sheng-ce Tao. The Binding Epitope of Sintilimab on PD-1 Revealed by AbMap. Acta Biochimica et Biophysica Sinica 2021, 53 (5), 628–635.
(6) Huan Qi; Ming-liang Ma; Dan-yuan Lai; Yang Li; Fucheng Zhang; Sheng-ce Tao. Assessment and Comparison of Recombinant Proteins from Different Sources for the Detection of SARS-CoV-2 Infection by Using Protein Microarray. Acta Biochimica et Biophysica Sinica 2021, 53 (2), 262–264.
(7) Qi, H.; Ma, M. L.; Lai, D. Y.; Tao, S. C. Phage Display: An Ideal Platform for Coupling Protein to Nucleic Acid. Acta Biochim. Biophys. Sin. 2021, 53 (4), 389–399.
(8) Qi, H.; Wang, F.; Tao, S. C. Proteome Microarray Technology and Application: Higher, Wider, and Deeper. Expert Rev. Proteomics 2019, 16 (10), 815–827.
(9) Qi, H.; Huiqiong Zhou; Daniel Mark Czajkowsky; Shujuan Guo; Yang Li; Nan Wang; Yi Shi; Lifeng Lin; Jingfang Wang; De Wu; Sheng-Ce Tao. Rapid Production of Virus Protein Microarray Using Protein Microarray Fabrication through Gene Synthesis (PAGES). Mol. Cell. Proteomics 2016, 16 (2), 288–299.
(10) Qi, H.; Wang, F.; Petrenko, V. A.; Liu, A. H. Peptide Microarray with Ligands at High Density Based on Symmetrical Carrier Landscape Phage for Detection of Cellulase. Anal. Chem. 2014, 86 (12), 5844–5850.
(11) Huan Qi; Fali Bai; Aihua Liu. Purification and Characteristics of Xyloglucanase and Five Other Cellulolytic Enzymes from Trichoderma Reesei QM9414. Biochemisty(Moscow) 2013, 78 (4), 424–430.
(12) Huan Qi; Haiqin Lu; Hua-Ji Qiu; Valery A. Petrenko; Aihua Liu. Phagemid Vectors for Phage Display: Properties, Characteristics and Construction. J Mol Biol 2012, 417 (3), 129–143.
1. 国家自然科学基金面上项目、32271492、覆盖70万种突变的噬菌体展示肽库的构建及基于该库的肿瘤血清生物标志物发现研究、2023/01-2026/12、54万、在研、主持；
2. 国家重点研发计划子课题、2023YFC2307202、结核菌多组学生物标志物发现、2023/12-2026/11、30万、在研、参与；
3. 上海是自然科学基金、21ZR1432000、鉴定RBD区域的逃逸突变并探索其对新冠病毒的影响、2021/07-2024/06、20万、在研、主持；
4. 国家自然科学基金青年基金、31600672、基于共有序列、全基因合成的登革病毒蛋白质芯片快速构建及其应用、2017/01-2019/12、19万、已结题、主持；
5. 中国博士后科学基金、2016M591667、蛋白质芯片快速构建技术及在登革病毒研究中的应用、2016/07-2017/06、5万、已结题、主持
一种快速获得抗原特异性抗体的方法 CN201710943109.2
一种蛋白质芯片的快速制备方法 CN201610396739.8
