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Rapid and Accurate Detection of SARS-CoV‐2 Using an iPad-Controlled, High-Throughput, Portable, and Multiplex Hive-Chip Platform (HiCube)
发布时间:2023/05/11

On April 24, 2023, Sheng-ce Tao group of Shanghai Jiao Tong University and Hong-ping Wei group of Wuhan Institute of Virology published an article entitled " Rapid and Accurate Detection of SARS-CoV‐2 Using an iPad- Controlled, High-Throughput, Portable, and Multiplex Hive-Chip Platform (HiCube)" in ACS Sensors (IF=9.618). By combining Hive-Chip (capillary microarray) and reverse transcriptional loop-mediated isothermal amplification (RT-LAMP), this article developed an iPad-controlled, high-throughput (48 samples at one run), portable (smaller than a backpack), multiplex (monitoring 8 gene fragments in one reaction), and real-time detection platform for SARS-CoV-2 detection. This platform is composed of a portable Hive-Chip device (HiCube; 32.7 × 29.7 × 20 cm, 5 kg), custom-designed software, and optimized Hive-Chips. 

 

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