Including learning experience
1996-1999 Dalian University of Technology, PhD degree
1991-1994 Dalian University of Technology, master degree
1987-1991 Dalian University of Technology, bachelor's degree

 

Work Experience
2011-present, Shanghai Jiao Tong University
2004-2010 Shanghai Institute of Applied Physics, CAS
2002-2004 Colorado State University, US
1999-2002 Shanghai Institute of Organic Chemistry, CAS
1994-1996 Dalian Institute of Chemical Physics, CAS

 

Talent Awards
2005 Hundred Talent Program; 38 women red flag bearers

 

DNA Sequencing By Synthesis Technology Program; Gene drug delivery system; development of nucleotide synthesis method

1. Qinglai Yang, Ling Bai, Yuanqing Zhang, Fangxia Zhu, Yuhong Xu, Zhifeng Shao, Yu-Mei Shen*, Bing Gong* ，Dynamic Covalent Block Copolymers: Instructed Coupling, Micellation and Redox Responsiveness；Macromolecules 2014, 47, 7431-7441.
2. Qinglai Yang, Changyu He, Yuhong Xu, Bingya Liu, Zhifeng Shao, Zhenggang Zhu, Yongtai Hou, Bing Gong and Yu-Mei Shen*，Chitosan oligosaccharide copolymer micelles with double disulphide linkage associated by H-bonding duplexes for targeted intracellular drug delivery ; Polymer Chemistry 2015, 6, 1454-1464.
3. Qinglai Yang, Lianjiang Tan, Changyu He, Bingya Liu, Yuhong Xu, Zhenggang Zhu, Zhifeng Shao, Bing Gong, Yu-Mei Shen* , Redox-Responsive Micelles Self-assembled from Dynamic Covalent Block Copolymers for Intracellular Drug Delivery; Acta Biomaterialia 2015, 17, 193-200.
4. Lianjiang Tan, Yazhi Liu, Qinglai Yang, Xiaowei Li, Xin-Yan Wu, Bing Gong, Yu-Mei Shen*, Zhifeng Shao , Design and synthesis of fluorescence-labelled nucleotide with azo cleavable linkers for DNA sequencing ; Chem. Commun., 2016, 52, 954-957.
5. Lianjiang Tan, Yazhi Liu, Xiaowei Li, Xin-Yan Wu, Bing Gong, Yu-Mei Shen*, Zhifeng Shao , Design and synthesis of an acid-cleavable, fluorescently labeled nucleotide as a reversible terminator for DNA sequencing ; Chem. Commun., 2016, 52, 2549-2552.
6. Wei Hu, Changyu He, Lianjiang Tan, Bingya Liu, Zhenggang Zhu, Bing Gong, Yu-Mei Shen*, Zhifeng Shao , Synthesis and Micellization of Redox-Responsive Dynamic Covalent Multi-block Copolymers; Polymer Chemistry 2016, 7, 3145-3155.
7. Changyu He, Zhen Zhang, Qinglai Yang, Qing Chang, Bing Gong, Zhifeng Shao, Yu-Mei Shen*, Bingya Liu*, Zhenggang Zhu , Reductive triblock copolymer with dynamic covalent linkage delivers antimiR-21 for gastric cancer’s treatment ; Polymer Chemistry 2016, 7, 4352-4366.
8. Lianjiang Tan*, Ran Huang, Xiaoqiang Li, Yu-Mei Shen*, Zhifeng Shao , Chitosan-based core-shell nanomaterials for pH-triggered release of anticancer drug and near-infrared bioimaging；Carbohydrate Polymers 2017, 157, 325-334.
9. Lianjiang Tan*, Ran Huang, Xiaoqiang Li, Shuiping Liu, Yu-Mei Shen* , Controllable release of nitric oxide and doxorubicin from engineered nanospheres for synergistic tumor therapy ; Acta Biomaterialia, 2017, 57, 498-510.
10. Jingwen Shi, Shuiping Liu, Yuan Yu, Changyu He, Lianjiang Tan*, Yu-Mei Shen*, RGD peptide-decorated micelles assembled from polymer−paclitaxel conjugates towards gastric cancer therapy; Colloids and Surfaces B:Biointerfaces 2019, 180, 58-67.

1. NSFC 22274099, 81671802, 81071250
2. Shanghai Jiao Tong University STAR Major Project - Development of DNA Sequencing Technology
3. State Project For Essential Drug Research and Development – Development of drug delivery system based on chitosan

Synthesis and Applications of acid cleavable linkers in DNA Sequencing 201410186697.6
1. DNA Sequencing system and Apparent of four color reversible terminators 201810308292.3
2. DNA single molecule sequencing method and sequencing system 201711280069.4
3. DNA sequencing by synthesis method and sequencing system 201711279201.X
4. DNA single molecule sequencing method and sequencing system based on reversible terminator of triazene derivatives 202011286386.9

Graduated five PhD students and eight master’s degree students, three of the PhD students have already been professors in famous university.