Including learning experience
PhD from the State University of New York at Stony Brook and the Cold Spring Harbor Laboratory, USA

 

 

Talent Awards
Executive vice director of MOE Key Laboratory of Systems Biomedicine, Investigator of State Key Laboratory of Oncogenes and Related Genes. Principle scientist of National Program on Key Basic Research Projects, State Department special allowance expert, Shanghai excellent academic leader. Won the first prize of natural science from Shanghai and the Ministry of Education of China, respectively. Professional committee member of the Gene Editing Branch of the Chinese Genetics Society and the Epigenetic Branch of the Chinese Cellular Society, Lifetime membership of the Sino-American Society of Life Scientists.

 

（1）Synthesis editing, folding mechanism and functional research of 3D genome；
（2）Function and regulation of Protocadherin in brain development；
（3）Function and regulation of UGT in drug metabolism.

（1）CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell（2015）
（2）Precise and Predictable CRISPR Chromosomal Rearrangements Reveal Principles of Cas9-Mediated Nucleotide Insertion，Molecular Cell （2018）
（3）Tandem CTCF sites function as insulators to balance spatial chromatin contacts and topological enhancer-promoter selection. Genome Biology (2020)
（4）Systematic functional characterization of antisense eRNA of protocadherin α composite enhancer. Genes & Development（2021）