科学研究
运动转化医学中心

发布时间:2018/12/07

成立日期:2018.05.26

中心主任:程蜀琳

 

中心成员:

访问学者2名:Petri Wiklund,Moritz Schumann

博士后3名:Xiaowei Ojanen、张媛、张美珍

行政人员1名:张涛

 

中心简介:

“运动转化医学中心”旨在聚焦慢性病运动康复研究,以自身科研团队建设为核心和基础,融合学校附属医院资源,利用国内各体育管理部门和科研机构及企业力量,联合国际一流运动医学研究机构和人员,为慢性病防治、全民健康促进、科学健身和政府决策提供科学依据。

三个基础研究方向:运动与药物治疗糖尿病最佳时效性与机制、运动对脂代谢影响的组织特异性、代谢病患者骨的理化特性。

三个应用研究方向:糖尿病运动处方、脂肪肝运动处方、骨关节病运动处方。

 

发表论文:

1. Cheng S, Wiklund P. The effects of muscle mass and muscle quality on cardio-metabolic risk in peripubertal girls: a longitudinal study from childhood to early adulthood. International Journal of Obesity (Lond). 2018 Apr;42(4):648-654. doi: 10.1038/ijo.2017.267. Epub 2017 Oct 30.

2. Huang T, Lu CY, Schumann M, Le SL, Yang YF, Zhuang HH, Lu QW, Liu JS, Wiklund P, Cheng S. Timing of exercise affects glycemic control in type 2 diabetes patients treated with metformin. Journal of Diabetes Research. 2018 Mar 29;2018:2483273. doi: 10.1155/2018/2483273. eCollection 2018.

3. Yang YF, Shi Y, Wiklund P, Tan X, Wu N, Zhang XB, Tikkanen O, Zhang CH, Munukka E, Cheng S. The Association between Cardiorespiratory Fitness and Gut Microbiota Composition in Premenopausal Women. Nutrients, vol. 9, no. 8, Aug, 2017. doi: 10.3390/nu9080792.

4. Zhang XB, Wiklund P, Wu N, Yang YF, Zhuang HH, Cheng S. 2017. Association of Leisure Time Physical Activity and NMR- Detected Circulating Amino Acids in Peripubertal Girls: a 7.5-Year Longitudinal Study. Scientific Reports, October. Springer US, 1–7. doi:10.1038/s41598-017-14116-2.

5. Wiklund P, Tormakangas T, Shi Y, Wu N, Vainionpaa A, Alen M, Cheng S. Normal-Weight Obesity and Cardiometabolic Risk: A 7-Year Longitudinal Study in Girls from Prepuberty to Early Adulthood. Obesity, vol. 25, no. 6, pp. 1077-1082, Jun, 2017.

6. Cheng S, Ge J, Zhao C, Le S, Yang Y, Ke D, Wu N, Tan X, Zhang X, Du X, Sun J, Wang R, Shi Y, Borra RJH, Parkkola R, Wiklund P, Lu D, Effect of aerobic exercise and diet on liver fat in pre-diabetic patients with non-alcoholic-fatty-liver-disease: A randomized controlled trial, Scientific Reports, 7(1):15952. doi: 10.1038/s41598-017-16159-x, Nov 2017.

7. Wiklund P, Zhang X, Pekkala S, Autio R, Kong L, Yang Y, Keinänen-Kiukaanniemi S, Alen M, Cheng S. Insulin resistance is associated with altered amino acid metabolism and adipose tissue dysfunction in normoglycemic women. Sci Rep. 2016 Apr 15;6:24540. doi: 10.1038/srep24540.

8. Wiklund P, Zhang X, Tan X, Keinänen-Kiukaanniemi S, Alen M, Cheng S. Serum Amino Acid Profiles in Childhood Predict Triglyceride Level in Adulthood: A 7-Year Longitudinal Study in Girls. J Clin Endocrinol Metab. 2016 May;101(5):2047-55. doi: 10.1210/jc.2016-1053.

9. S, Degens H, Evans M, Cheng SM, Selänne H, Rittweger J, Heinonen A, Suominen H, Strandberg T, Alen M, Korhonen MT. What Makes a 97-Year-Old Man Cycle 5,000 km a Year? Gerontology. 2016;62(5):508-12. doi: 10.1159/000443390.

10. Tan X, Alén M, Wang K, Tenhunen J, Wiklund P, Partinen M, Cheng S. Effect of Six-Month Diet Intervention on Sleep among Overweight and Obese Men with Chronic Insomnia Symptoms: A Randomized Controlled Trial. Nutrients. 2016 Nov 23;8(11). pii: E751.

11. Munukka E, Wiklund P, Partanen T, Välimäki S, Laakkonen EK, Lehti M, Fischer-Posovszky P, Wabitsch M, Cheng S, Huovinen P, Pekkala S. Adipocytes as a Link Between Gut Microbiota-Derived Flagellin and Hepatocyte Fat Accumulation. PLoS One. 2016 Apr 1;11(4):e0152786. doi: 10.1371/journal.pone.0152786. eCollection 2016. Erratum in: PLoS One. 2016;11(6):e0157254.

12. Le S, Mao L, Lu D, Yang Y, Tan X, Wiklund P, Cheng S. Effect of aerobic exercise on insulin resistance and central adiposity disappeared after the discontinuation of intervention in overweight women. JSHS 5 (2016) 166–170.

13. Tan X, Alén A, Wiklund P, Partinen M, Cheng S. Effects of aerobic exercise on home-based sleep among overweight and obese men with chronic insomnia symptoms: a randomized controlled trial. Sleep Medicine (2016), http://dx.doi.org/doi: 10.1016/j.sleep.2016.02.010.

 

Copyright © 2016 上海交大系统生物医学研究院 版权所有
分享到

地址:上海市东川路800号
邮编:200240
电话:021-34206059